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Milestone Payment Milestone payment Liabilities and Equity Total liabilities and stockholders' equity Payables and Accruals [Abstract] Proceeds from the Subscription Agreement, net of offering costs Proceeds from the Subscription Agreement, net of offering costs Proceeds from the Subscription Agreement, net of offering costs of $2,000 Long-Lived Tangible Asset [Axis] Finance Lease, Liability, to be Paid, Year Three Thereafter Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Valuation allowance deferred tax asset change in amount Conversion of convertible preferred stock  to common stock. Conversion Of Convertible Preferred Stock To Common Stock Conversion of Convertible Preferred Stock to Common Stock Conversion of Convertible Preferred Stock to Common Stock Cybersecurity Risk Third Party Oversight and Identification Processes [Flag] Business combination transaction costs payable current. 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Deferred Tax Assets Capitalized Start Up And Organizational Costs Capitalized research and development expenses Proceeds From Convertible Debt Proceeds from Convertible Debt Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration Deferred tax assets operating loss carryforwards not subject to expiration Geographical [Domain] Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Cash, Cash Equivalents, Restricted Cash, and Concentration of Credit Risk Defined Contribution Plan [Abstract] Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less) [Abstract] Defined Contribution Plan, Employer Matching Contribution, Percent of Employees' Gross Pay Defined contribution plan employee mathing contribution percentage Total undiscounted cash flows Lease Liability Payments Due Lease Liability Payments Due Reverse Stock Split and Exchange Ratio Reverse Stock Split and Exchange Ratio [Policy Text Block] Reverse Stock Split and Exchange Ratio [Policy Text Block] Defined Contribution Plan [Text Block] Employee Benefit Plan Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Property, Plant and Equipment [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Options Granted, Number of Shares Alloy therapeutics, Llc. 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Cash Paid for Amounts included in the Measurement of Lease Liabilities [Abstract] Cash paid for amounts included in the measurement of lease liabilities Deferred Income Tax Expense (Benefit) Deferred income tax expense benefit Deferred Tax Benefit Sale of Stock, Number of Shares Issued in Transaction Shares issued under securities purchase agreement Stock Issued During Period, Shares, New Issues Stock issued during the period shares new issues Lease, Cost [Abstract] Temporary Equity, Shares Authorized Preferred stock, authorized Share Based Compensation Arrangement By Share Based Payment Equity Instruments Other Than Options Unvested And Expected To Vest Weighted Average Grant Date Fair Value Share Based Compensation Arrangement By Share Based Payment Equity Instruments Other Than Options Unvested And Expected To Vest Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Unvested and expected to vest as of December 31, 2025 Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Vested Business Combination [Abstract] Earnings Per Share, Diluted Net loss per share, diluted Net loss per share, diluted Schedule of Segment Reporting Information, by Segment [Table Text Block] Schedule of segment net loss and significant segment expenses Operating Segments [Member] Percent Effective Income Tax Rate Reconciliation, Percent [Abstract] Deferred Tax Liabilities Right Of Use Assets Deferred Tax Liabilities Right Of Use Assets Right of use asset Right of use asset Title and Position [Domain] Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration] City Area Code Auditor Name Finance Lease, Liability, Noncurrent Finance Lease Liability Non-current Finance lease liability, non-current Counterparty Name [Domain] Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount Federal R&D credit amount Effective Income Tax Rate Reconciliation, Nondeductible Expense, Impairment Losses, Percent SAFE liability loss percent Variable Lease, Cost Variable lease expense Operating Lease, Weighted Average Remaining Lease Term Operating leases Segment Reporting Information [Line Items] Stock split, conversion ratio Stockholders' Equity Note, Stock Split, Conversion Ratio Lease Expiration Date Lease Expiration Date Retirement Plan Name [Axis] Unrestricted Common Stock [Member] Property, Plant and Equipment, Net Property and equipment, net Property and equipment, net Deferred Foreign Income Tax Expense (Benefit) Foreign Deferred Expense Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Options vested and exercisable as of December 31, 2025 Operating Income (Loss) Loss from operations Retained Earnings [Member] Accumulated Deficit [Member] Cash and Cash Equivalents [Axis] Share-Based Compensation Arrangements by Share-Based Payment Award, Restricted Stock Units, Vested and Expected to Vest [Table Text Block] Summary of the unrecognized compensation expense and weighted-average remaining period Employee Benefits and Share-Based Compensation Stock Compensation Expense Share-Based Payment Arrangement, Noncash Expense Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense, Total Unamortized Expense Conversion of stock shares percentage. Conversion of Stock Shares Percentage Conversion of stock shares percentage Operating Lease, Weighted Average Discount Rate, Percent Operating leases Operating Lease, Liability, Noncurrent Operating lease liability Non-current Operating lease liability, non-current Fair Value, Inputs, Level 1 [Member] Fair Value, Inputs, Level 1 [Member] Class of Stock [Line Items] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash provided by financing activities Schedule of Components of Lease Expense and Other Information Lease, Cost [Table Text Block] Nontaxable or nondeductible items: Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent [Abstract] Auditor Location Nonoperating Income (Expense) [Abstract] Other income (expense): Issuance Of Common Stock Upon The Merger Value Issuance of common stock upon the merger value. Issuance of common stock upon the merger AVRO Avrobio common stock. AVRO Avrobio Common Stock [Member] AVRO Avrobio Common Stock [Member] Non-ClinicalScienceExpenses[Member] Non-ClinicalScienceExpenses[Member] Repurchase Liability For Restricted Common Stock Repurchase Liability For Restricted Common Stock Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Summary of Diluted Net Loss Per Share Attributable to Common Stockholders Deferred Tax Assets, Operating Loss Carryforwards, Foreign Foreign Net Operating loss Carryforwards Non refundable license fee shares fair value. Non Refundable License Fee Shares Fair Value Non refundable license fee shares fair value Rule10b5-1 Arrangement Modified [Flag] Rule 10b51 Arr Modified Flag Rule 10b51 Arr Modified Flag Income Tax Authority [Domain] Entity Interactive Data Current Income Statement Location [Domain] Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Cash flows from operating activities: Furniture and Fixtures [Member] Office equipment, furniture and fixtures [Member] Common Stock, Dividends, Per Share, Declared Common stock, dividends, per share, declared Entity Tax Identification Number Adjusted balance beginning of period value. Adjusted Balance Beginning Of Period Value Adjusted balance, beginning of period Non refundable and non creditable annul fee. Non RefundableAnd Non Creditable Annul Fee Non refundable and non creditable annul fee Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Effect of exchange rate changes on cash and cash equivalents Share based compensation by share based award equity instruments other than options repurchase liability current. Share Based Compensation by Share Based Award Equity Instruments Other than Options Repurchase Liability Current Share based compensation by share based award equity instruments other than options equity repurchase liability current Payment of non refundable license fee amount. Payment Of Non RefundableLicense Fee Amount Payment of non refundable license fee amount Proceeds from Issuance or Sale of Equity Proceeds from Issuance or Sale of Equity, Total Local Phone Number Financial Instruments Subject to Mandatory Redemption, Financial Instrument [Domain] Related Party Transaction [Domain] Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Share based compensation by share based award equity instruments other than options unvested and outstanding unrecognized compensation Short-Term Lease, Cost Short-term lease expense Auditor Opinion [Text Block] Auditor Opinion Finance Lease, Liability, to be Paid, Year Two 2027 Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Net of offering costs Simple agreements for future equity. Simple Agreements for Future Equity [Member] SAFEs (as converted to common stock) [Member] SAFE [Member] Accounting Policies [Abstract] Other Current Liabilities [Member] Other Sundry Liabilities, Current Amount Due to Related Party Amount Due to Related Party Net Income (Loss) Attributable to Parent [Abstract] Proceeds from simple agreement for future equity. Proceeds From Simple Agreement For Future Equity Proceeds from the issuance of SAFEs Class of Stock [Domain] Future Minimum Lease Payments Operating Leases, Future Minimum Payments Due Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Share-based payment arrangement, nonvested award, cost not yet recognized, period for recognition Office Equipment [Member] Laboratory equipment [Member] Accrued Professional Fees, Current Accrued other expenses Two Thousand Nineteen And Two Thousand Twenty Four [Member] Two Thousand Nineteen And Two Thousand Twenty Four Member 2019 and 2024 Employee Stock Purchase Plan [Member] Lease Liability Payments Due Next Twelve Months Lease Liability Payments Due Next Twelve Months 2026 Schedule of Stock by Class [Table] Entity Emerging Growth Company Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Weighted-Average Remaining Contractual Term (Years) Unvested and expected to vest as of December 31, 2025 AVROBIO. AVROBIO [Member] AVROBIO Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less), and Goodwill Net assets acquired Tax Credit Carryforward, Name [Domain]