1001 - Document - Cover Page link:presentationLink link:definitionLink link:calculationLink 1002 - Statement - Consolidated Balance Sheets link:presentationLink link:definitionLink link:calculationLink 1003 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:definitionLink link:calculationLink 1004 - Statement - Consolidated Statements Of Operations And Comprehensive Income (Loss) link:presentationLink link:definitionLink link:calculationLink 1005 - Statement - Consolidated Statements of Stockholders' Equity link:presentationLink link:definitionLink link:calculationLink 1006 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:definitionLink link:calculationLink 1007 - Disclosure - Nature of the Business link:presentationLink link:definitionLink link:calculationLink 1008 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:definitionLink link:calculationLink 1009 - Disclosure - License and Purchase Agreements link:presentationLink link:definitionLink link:calculationLink 1010 - Disclosure - Fair Value of Financial Assets and Liabilities link:presentationLink link:definitionLink link:calculationLink 1011 - Disclosure - Supplemental Balance Sheet Information link:presentationLink link:definitionLink link:calculationLink 1012 - Disclosure - Leases link:presentationLink link:definitionLink link:calculationLink 1013 - Disclosure - Note Payable link:presentationLink link:definitionLink link:calculationLink 1014 - Disclosure - Common Stock link:presentationLink link:definitionLink link:calculationLink 1015 - Disclosure - Stock-Based Compensation link:presentationLink link:definitionLink link:calculationLink 1016 - Disclosure - 401(k) Savings Plan link:presentationLink link:definitionLink link:calculationLink 1017 - Disclosure - Commitments and Contingencies link:presentationLink link:definitionLink link:calculationLink 1018 - Disclosure - Income Taxes link:presentationLink link:definitionLink link:calculationLink 1019 - Disclosure - Net Income (Loss) per Share link:presentationLink link:definitionLink link:calculationLink 1020 - Disclosure - Related Party Transactions link:presentationLink link:definitionLink link:calculationLink 1021 - Disclosure - Restructuring link:presentationLink link:definitionLink link:calculationLink 1022 - Disclosure - Subsequent Events link:presentationLink link:definitionLink link:calculationLink 1023 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:definitionLink link:calculationLink 1024 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:definitionLink link:calculationLink 1025 - Disclosure - Fair Value of Financial Assets and Liabilities (Tables) link:presentationLink link:definitionLink link:calculationLink 1026 - Disclosure - Supplemental Balance Sheet Information (Tables) link:presentationLink link:definitionLink link:calculationLink 1027 - Disclosure - Leases (Tables) link:presentationLink link:definitionLink link:calculationLink 1028 - Disclosure - Note Payable (Tables) link:presentationLink link:definitionLink link:calculationLink 1029 - Disclosure - Common Stock (Tables) link:presentationLink link:definitionLink link:calculationLink 1030 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:definitionLink link:calculationLink 1031 - Disclosure - Income Taxes (Tables) link:presentationLink link:definitionLink link:calculationLink 1032 - Disclosure - Net Income (Loss) per Share (Tables) link:presentationLink link:definitionLink link:calculationLink 1033 - Disclosure - Restructuring (Tables) link:presentationLink link:definitionLink link:calculationLink 1034 - Disclosure - Nature of the Business - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1035 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1036 - Disclosure - Summary of Significant Accounting Policies - Schedule of Property and Equipment Estimated Useful Life (Detail) link:presentationLink link:definitionLink link:calculationLink 1037 - Disclosure - License and Purchase Agreements - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1038 - Disclosure - Fair Value of Financial Assets and Liabilities - Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Detail) link:presentationLink link:definitionLink link:calculationLink 1039 - Disclosure - Fair Value of Financial Assets and Liabilities - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1040 - Disclosure - Supplemental Balance Sheet Information - Summary of Prepaid Expenses and Other Current Assets (Detail) link:presentationLink link:definitionLink link:calculationLink 1041 - Disclosure - Supplemental Balance Sheet Information - Summary of Property and Equipment, Net (Detail) link:presentationLink link:definitionLink link:calculationLink 1042 - Disclosure - Supplemental Balance Sheet Information - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1043 - Disclosure - Supplemental Balance Sheet Information - Summary of Restricted Cash (Detail) link:presentationLink link:definitionLink link:calculationLink 1044 - Disclosure - Supplemental Balance Sheet Information - Summary of Accrued Expenses (Detail) link:presentationLink link:definitionLink link:calculationLink 1045 - Disclosure - Leases - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1046 - Disclosure - Leases - Schedule of effective lease cost comprehensive income loss (Details) link:presentationLink link:definitionLink link:calculationLink 1047 - Disclosure - Leases - Summary of Future Minimum Lease Payments Due Under Operating Leases (Details) link:presentationLink link:definitionLink link:calculationLink 1048 - Disclosure - Note Payable - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1049 - Disclosure - Note Payable - Carrying Value of Note Payable (Details) link:presentationLink link:definitionLink link:calculationLink 1050 - Disclosure - Common Stock - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1051 - Disclosure - Common Stock - Summary of Common Stock Reserved for Future Issuance (Detail) link:presentationLink link:definitionLink link:calculationLink 1052 - Disclosure - Stock-Based Compensation - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1053 - Disclosure - Stock-Based Compensation - Summary of Assumptions that Used to Determine Grant-Date Fair Value of Stock Options Granted to Employees and Members of Board (Detail) link:presentationLink link:definitionLink link:calculationLink 1054 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activity (Detail) link:presentationLink link:definitionLink link:calculationLink 1055 - Disclosure - Stock-Based Compensation - Summary of Restricted Stock Award and Restricted Stock Unit Activity (Detail) link:presentationLink link:definitionLink link:calculationLink 1056 - Disclosure - Stock-Based Compensation - Schedule of Stock-based Compensation Expense (Detail) link:presentationLink link:definitionLink link:calculationLink 1057 - Disclosure - 401(k) Savings Plan - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1058 - Disclosure - Income Taxes - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1059 - Disclosure - Income Taxes - Schedule of Reconciliation of Income Tax Expense (Benefit) (Detail) link:presentationLink link:definitionLink link:calculationLink 1060 - Disclosure - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Detail) link:presentationLink link:definitionLink link:calculationLink 1061 - Disclosure - Net Income (Loss) Per Share - Components of Basic and Diluted Earnings Per Share (Details) link:presentationLink link:definitionLink link:calculationLink 1062 - Disclosure - Net Income (Loss) Per Share - Schedule of Dilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss per Share (Detail) link:presentationLink link:definitionLink link:calculationLink 1063 - Disclosure - Related Party Transactions - Additional Information (Detail) link:presentationLink link:definitionLink link:calculationLink 1064 - Disclosure - Restructuring - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1065 - Disclosure - Restructuring - Schedule of Restructuring Activities (Details) link:presentationLink link:definitionLink link:calculationLink 1066 - Disclosure - Subsequent Events - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink