Entity Central Index Key Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Entity Emerging Growth Company Entity Emerging Growth Company Entity Ex Transition Period Entity Ex Transition Period Entity Small Business Entity Small Business Entity Current Reporting Status Entity Current Reporting Status Entity Shell Company Entity Shell Company Entity File Number Entity File Number Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address Address Line1 Entity Address, Address Line Two Entity Address Address Line2 Entity Address, Address Line Three Entity Address Address Line3 Entity Address, City or Town Entity Address City Or Town Entity Address, State or Province Entity Address State Or Province Entity Address, Postal Zip Code Entity Address Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Document Quarterly Report Document Quarterly Report Document Transition Report Document Transition Report Entity Incorporation, State or Country Code Entity Incorporation State Country Code Entity Interactive Data Current Entity Interactive Data Current Title of 12(b) Security Security12b Title Security Exchange Name Security Exchange Name Statement Of Financial Position [Abstract] Assets Assets [Abstract] Current assets: Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Prepaid expenses and other current assets Prepaid Expense And Other Assets Current Total current assets Assets Current Property and equipment, net Property Plant And Equipment Net Restricted cash Restricted Cash Noncurrent Other assets Other Assets Noncurrent Total assets Assets Liabilities and stockholders’ equity Liabilities And Stockholders Equity [Abstract] Current liabilities: Liabilities Current [Abstract] Accounts payable Accounts Payable Current Accrued expenses and other current liabilities Accrued Liabilities Current Deferred rent Deferred Rent Credit Current Total current liabilities Liabilities Current Deferred rent, net of current portion Deferred Rent Credit Noncurrent Total liabilities Liabilities Commitments and contingencies (Note 6) Commitments And Contingencies Stockholders’ equity: Stockholders Equity [Abstract] Preferred stock, $0.0001 par value; 10,000 shares authorized; no shares issued or outstanding Preferred Stock Value Common stock, $0.0001 par value; 150,000 shares authorized; 43,632 and 41,569 shares issued and outstanding as of September 30, 2021 and December 31, 2020, respectively Common Stock Value Additional paid-in capital Additional Paid In Capital Common Stock Accumulated deficit Retained Earnings Accumulated Deficit Total stockholders’ equity Stockholders Equity Total liabilities and stockholders’ equity Liabilities And Stockholders Equity Preferred stock, par value Preferred Stock Par Or Stated Value Per Share Preferred stock, authorized Preferred Stock Shares Authorized Preferred stock, issued Preferred Stock Shares Issued Preferred stock, outstanding Preferred Stock Shares Outstanding Common stock, par value Common Stock Par Or Stated Value Per Share Common stock, authorized Common Stock Shares Authorized Common stock, issued Common Stock Shares Issued Common stock, outstanding Common Stock Shares Outstanding Statement Of Income And Comprehensive Income [Abstract] Operating expenses: Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Total operating expenses Operating Expenses Loss from operations Operating Income Loss Other (expense) income: Nonoperating Income Expense [Abstract] Interest income Investment Income Interest Other income (expense) Other Nonoperating Income Expense Total other (expense) income, net Nonoperating Income Expense Net loss Net Income Loss Comprehensive loss Comprehensive Income Net Of Tax Net loss per share — basic and diluted Earnings Per Share Basic And Diluted Weighted-average number of common shares outstanding — basic and diluted Weighted Average Number Of Share Outstanding Basic And Diluted Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Class of Stock Statement Class Of Stock [Axis] Class of Stock Class Of Stock [Domain] Common Stock [Member] Common Stock [Member] Additional Paid-in Capital [Member] Additional Paid In Capital [Member] Accumulated Deficit [Member] Retained Earnings [Member] Sale of Stock Subsidiary Sale Of Stock [Axis] Sale of Stock Sale Of Stock Name Of Transaction [Domain] Public Offering [Member] I P O [Member] At-the-market Facility. ATM Facility [Member] At The Market Facility [Member] Statement [Line Items] Statement [Line Items] Beginning balance Beginning balance, shares Shares Outstanding Stock-based compensation expense Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Exercise of stock options Stock Issued During Period Value Stock Options Exercised Exercise of stock options, shares Stock Issued During Period Shares Stock Options Exercised Vesting of restricted stock awards and units Stock Issued During Period Value Restricted Stock Award Gross Vesting of restricted stock awards and units, shares Stock Issued During Period Shares Restricted Stock Award Gross Issuance of common stock, net of offering costs Stock Issued During Period Value New Issues Issuance of common stock upon public offering, net of offering costs, shares Stock Issued During Period Shares New Issues Issuance of common stock under the 2018 employee stock purchase plan Stock Issued During Period Value Employee Stock Purchase Plan Issuance of common stock under the 2018 employee stock purchase plan, shares Stock Issued During Period Shares Employee Stock Purchase Plans Net loss Ending balance Ending balance, shares Issuance of common stock upon public offering, offering costs Adjustments To Additional Paid In Capital Stock Issued Issuance Costs Deferred rent expense. Statement Of Cash Flows [Abstract] ESPP [Member] Employee Stock [Member] Cash flows from operating activities: Net Cash Provided By Used In Operating Activities [Abstract] Net loss Profit Loss Adjustments to reconcile net loss to net cash used in operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Depreciation and amortization expense Depreciation Depletion And Amortization Stock-based compensation expense Share Based Compensation Deferred rent expense Deferred Rent Expense Changes in operating assets and liabilities: Increase Decrease In Operating Capital [Abstract] Prepaid expenses and other current assets Increase Decrease In Prepaid Deferred Expense And Other Assets Other assets Increase Decrease In Other Operating Assets Accounts payable Increase Decrease In Accounts Payable Accrued expenses and other current liabilities Increase Decrease In Accrued Liabilities And Other Operating Liabilities Net cash used in operating activities Net Cash Provided By Used In Operating Activities Cash flows from investing activities: Net Cash Provided By Used In Investing Activities [Abstract] Purchases of property and equipment Payments To Acquire Property Plant And Equipment Net cash used in investing activities Net Cash Provided By Used In Investing Activities Cash flows from financing activities: Net Cash Provided By Used In Financing Activities [Abstract] Proceeds from exercise of stock options Proceeds From Stock Options Exercised Proceeds from issuance of common stock Proceeds From Issuance Of Common Stock Payment of offering costs Payments Of Stock Issuance Costs Net cash provided by financing activities Net Cash Provided By Used In Financing Activities Net (decrease) increase in cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Cash, cash equivalents and restricted cash at beginning of period Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Restricted cash Restricted Cash Cash, cash equivalents and restricted cash at end of period Supplemental disclosure of non-cash investing and financing activities: Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Purchases of property and equipment included in accounts payable and accrued expenses Capital Expenditures Incurred But Not Yet Paid Reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheets: Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Excluding Exchange Rate Effect [Abstract] Cash and cash equivalents, end of period Restricted cash Organization Consolidation And Presentation Of Financial Statements [Abstract] Nature of the Business Nature Of Operations Accounting Policies [Abstract] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] License agreement disclosure. License agreements. License Agreements [Abstract] License Agreements License Agreement Disclosure [Text Block] Fair Value Disclosures [Abstract] Fair Value Measurement Fair Value Disclosures [Text Block] Balance Sheet Related Disclosures [Abstract] Supplemental Balance Sheet Information Supplemental Balance Sheet Disclosures [Text Block] Commitments And Contingencies Disclosure [Abstract] Commitments and Contingencies Commitments And Contingencies Disclosure [Text Block] Equity [Abstract] Stockholders' Equity Stockholders Equity Note Disclosure [Text Block] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Stock-Based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Earnings Per Share [Abstract] Net Loss Per Share Earnings Per Share [Text Block] Related Party Transactions [Abstract] Related Party Transactions Related Party Transactions Disclosure [Text Block] Subsequent Events [Abstract] Subsequent Events Subsequent Events [Text Block] Basis of Presentation Basis Of Accounting Policy Policy [Text Block] Segment Information Segment Reporting Policy Policy [Text Block] Use of Estimates Use Of Estimates Stock-Based Compensation Compensation Related Costs Policy [Text Block] Emerging growth company status. Emerging Growth Company Status Emerging Growth Company Status Policy [Text Block] Subsequent Event Considerations Subsequent Events Policy Policy [Text Block] Recently Issued Accounting Pronouncements New Accounting Pronouncements Policy Policy [Text Block] Summary of Financial Assets Measured at Fair Value on Recurring Basis Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Table [Text Block] Summary of Prepaid Expenses and Other Current Assets Deferred Costs Capitalized Prepaid And Other Assets Disclosure [Text Block] Summary of Property and Equipment, Net Property Plant And Equipment [Text Block] Summary of Accrued Expenses Schedule Of Accrued Liabilities Table [Text Block] Summary of Common Stock Reserved for Future Issuance Schedule Of Stock By Class [Text Block] Summary of Assumptions that Used to Determine Grant-Date Fair Value of Stock Options Granted to Employees and Members of Board of Directors Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Summary of Stock Option Activity Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Summary of Restricted Common Stock Units Schedule Of Sharebased Compensation Restricted Stock And Restricted Stock Units Activity Table [Text Block] Schedule of Stock-based Compensation Expense Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Schedule of Dilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss per Share Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Net loss Accumulated deficit Significant Accounting Policies [Abstract] Significant Accounting Policies [Abstract] Number of operating segment Number Of Operating Segments Represents the amount of the upfront license fees. License agreement. License Agreement [Table] License Agreement [Table] License Agreement [Table] Counterparty Name Counterparty Name [Axis] Counterparty Name Repurchase Agreement Counterparty Name [Domain] University of Manchester agreement. University of Manchester Agreement [Member] University Of Manchester Agreement [Member] Collaborative Arrangement and Arrangement Other than Collaborative Type Of Arrangement [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Arrangements And Nonarrangement Transactions [Member] MPSII license agreement. MPSII License Agreement [Member] M P S I I License Agreement [Member] UHN agreement. UHN Agreement [Member] U H Nagreement [Member] Fabry license agreement. Fabry License Agreement [Member] Fabrylicenseagreement [Member] Interleukin 12 license agreement. Interleukin 12 License Agreement [Member] Interleukin12 License Agreement [Member] BioMarin Pharmaceutical Inc. BioMarin Pharmaceutical Inc [Member] Bio Marin Pharmaceutical Inc [Member] GenStem Therapeutics Inc. GenStem Therapeutics Inc [Member] Genstem Therapeutics Inc [Member] Lund University Rights Holders Agreement. Lund University Rights Holders Agreement [Member] Lund University Rights Holders Agreement [Member] License Agreement [Line Items] License Agreement [Line Items] Upfront license fee Upfront License Fees Milestone payment to be paid. Milestone payment paid. Milestone Payment Due Milestone payments payable Milestone Payment To Be Paid Milestone payment paid Milestone Payment Paid Milestone payment due Milestone Payment Due Agreement expiration period. Agreement expiration description. Agreement expiration period Agreement Expiration Period Agreement expiration description Agreement Expiration Description Clinical trial cost related to research and development expense. Research and development expense Clinical Trial Cost Related To Research And Development Expense Collaborative agreement expenses. Collaborative agreement expenses Collaborative Agreement Expenses Option fee. Option fee Option Fee Milestone fees. Milestone fees Milestone Fees License Maintenance Fees Payments upon closing of initial public offering. Annual maintenance fees License Maintenance Fees Fair value of shares issued Payments upon closing of an initial public offering Payments Upon Closing Of Initial Public Offering License Agreement Expenses Expenses related to license License Agreement Expenses Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Measurement Frequency Fair Value By Measurement Frequency [Axis] Measurement Frequency Fair Value Measurement Frequency [Domain] Fair Value on Recurring Basis [Member] Fair Value Measurements Recurring [Member] Level 2 [Member] Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Hierarchy and NAV Fair Value Measurements Fair Value Hierarchy [Domain] Level 1 [Member] Fair Value Inputs Level1 [Member] Level 2 [Member] Fair Value Inputs Level2 [Member] Level 3 [Member] Fair Value Inputs Level3 [Member] Asset Class Fair Value By Asset Class [Axis] Asset Class Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation By Asset Class [Domain] Money Market Funds [Member] Money Market Funds [Member] Cash and Cash Equivalents Cash And Cash Equivalents [Axis] Cash and Cash Equivalents Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member] Cash Equivalents [Member] Cash Equivalents [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Assets Fair Value Disclosure Assets Fair Value Disclosure [Abstract] Assets Fair Value Disclosure Assets Fair Value Disclosure The fair value input amount of assets and liabilities between levels. Fair value input transfer between levels Fair Value Input Amount Transfer Between Levels Tax incentive refund current . Prepaid research and development costs current. Prepaid compensation benefits. Supplemental balance sheet information disclosures. Supplemental Balance Sheet Information Disclosures [Abstract] Tax incentive refund Tax Incentive Refund Current Prepaid research and development expenses Prepaid Research And Development Costs Current Prepaid insurance Prepaid Insurance Prepaid compensation benefits Prepaid Compensation Benefits Other current assets Other Assets Current Total Disclosure - Supplemental Balance Sheet Information - Summary of Property and Equipment, Net (Detail) [Abstract] Disclosure Supplemental Balance Sheet Information Summary Of Property And Equipment Net Detail [Abstract] Schedule Of Property Plant And Equipment [Table] Schedule Of Property Plant And Equipment [Table] Long-Lived Tangible Asset Property Plant And Equipment By Type [Axis] Long-Lived Tangible Asset Property Plant And Equipment Type [Domain] Laboratory and Office Equipment [Member] Office Equipment [Member] Leasehold Improvements [Member] Leasehold Improvements [Member] Computer Equipment [Member] Computer Equipment [Member] Property Plant And Equipment [Line Items] Property Plant And Equipment [Line Items] Property plant and equipment, gross Property Plant And Equipment Gross Less: Accumulated depreciation and amortization Accumulated Depreciation Depletion And Amortization Property Plant And Equipment Property and equipment, net Accrued research and development expense current. Accrued Liabilities Current [Abstract] Compensation and benefit costs Employee Related Liabilities Current Research and development expenses Accrued Research And Development Expense Current Consulting and professional fees Accrued Professional Fees Current Other liabilities Other Accrued Liabilities Current Accrued expenses Undesignated preferred stock. Undesignated shares of preferred stock outstanding. Undesignated preferred stock Undesignated Preferred Stock Undesignated shares of preferred stock outstanding Undesignated Shares Of Preferred Stock Outstanding Cash dividends Dividends Cash Schedule Of Stock By Class [Table] Schedule Of Stock By Class [Table] 2018 stock option and incentive plan. 2018 Stock Option and Incentive Plan [Member] Two Thousand Eighteen Stock Option And Incentive Plan [Member] 2018 employee stock purchase plan. 2018 Employee Stock Purchase Plan [Member] Two Thousand Eighteen Employee Stock Purchase Plan [Member] Two Thousand Nineteen Inducements Plan. 2019 Inducement Plan [Member] Two Thousand Nineteen Inducements Plan [Member] Two thousand twenty inducements plan. 2020 Inducement Plan [Member] Two Thousand Twenty Inducements Plan [Member] Award Type Award Type [Axis] Award Type Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Employee Stock Option [Member] Employee Stock Option [Member] Restricted Stock Units [Member] Restricted Stock Units R S U [Member] Class Of Stock [Line Items] Class Of Stock [Line Items] Total shares of authorized common stock reserved for future issuance Common Stock Capital Shares Reserved For Future Issuance Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions And Methodology [Abstract] Expected option life (years) Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 Risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Expected volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Expected dividend yield Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Roll Forward Number of options, Outstanding beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Number of options, Granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Number of options, Exercised Number of options, Cancelled or forfeited Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Number of options, Outstanding ending balance Number of options, Exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Weighted average exercise price, Outstanding beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted average exercise price, Granted Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Weighted average exercise price, Exercised Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Weighted average exercise price, Cancelled or forfeited Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Weighted Average Exercise Price Weighted average exercise price, Outstanding ending balance Weighted average exercise price, Exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted average remaining contractual term, Outstanding balance Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Weighted average remaining contractual term, Exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1 Aggregate intrinsic value, Outstanding balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Aggregate intrinsic value, Exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Aggregate intrinsic value of options exercised Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value Options Granted, Weighted-average grant-date fair value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Share based compensation arrangement by share based payment award equity instruments other than options forfeited and expirations in period. Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Number of shares, Issued and unvested beginning balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number Number of shares, Granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Number of shares, Vested Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Number of shares, Forfeited, cancelled or expired Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited And Expirations In Period Number of shares, Issued and unvested ending balance Share based compensation arrangement by share based payment award equity instruments other than options forfeitures and expirations, weighted average grant date fair value. Weighted average grant date fair value, Issued and unvested, beginning balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value Weighted average grant date fair value, Granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value Weighted average grant date fair value, Vested Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value Weighted average grant date fair value, Forfeited, canceled or expired Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures And Expirations Weighted Average Grant Date Fair Value Weighted average grant date fair value, Issued and unvested, ending balance Total fair value of restricted stock units vested Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Total Fair Value Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Income Statement Location Income Statement Location [Axis] Income Statement Location Income Statement Location [Domain] Research and Development Expense [Member] Research And Development Expense [Member] General and Administrative Expense [Member] General And Administrative Expense [Member] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Total stock-based compensation expense Allocated Share Based Compensation Expense Unrecognized stock-based compensation expenses Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options Unrecognized stock-based compensation expense, period for recognition Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Antidilutive Securities Name [Domain] Options to Purchase Common Stock [Member] Restricted Stock Units [Member] Restricted Stock [Member] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive securities excluded from computation of earnings per share amount Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Schedule Of Related Party Transactions By Related Party [Table] Schedule Of Related Party Transactions By Related Party [Table] License agreement. License Agreement [Member] License Agreement [Member] Title of Individual Title Of Individual [Axis] Title of Individual Title Of Individual With Relationship To Entity [Domain] Officers and board members. Officers and Board Members [Member] Officers And Board Members [Member] Sub-lease agreement. Sub-lease Agreement [Member] Sublease Agreement [Member] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Research and development expense Expense related to related party Related Party Transaction Expenses From Transactions With Related Party Subsequent Event [Table] Subsequent Event [Table] Lender Name Line Of Credit Facility [Axis] Line of Credit Facility, Lender Line Of Credit Facility Lender [Domain] Silicon Valley Bank. Silicon Valley Bank [Member] Silicon Valley Bank [Member] Subsequent Event Type Subsequent Event Type [Axis] Subsequent Event Type Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event [Member] Credit Facility Credit Facility [Axis] Credit Facility Credit Facility [Domain] Term loan. Term Loan [Member] Term Loan [Member] Debt Instrument Debt Instrument [Axis] Debt Instrument, Name Debt Instrument Name [Domain] Clinical milestone prior to draw. Clinical Milestone Prior To Draw Clinical Milestone Prior To Draw [Member] Regulatory milestone prior to draw. Tranche A Draw Period [Member] Regulatory Milestone Prior To Draw [Member] Loan and security agreement. Loan and Security Agreement [Member] Loan And Security Agreement [Member] Term loan prepaid through November two two thousand twenty two. Term Loan Prepaid through November 2, 2022 [Member] Term Loan Prepaid Through November Two Two Thousand Twenty Two [Member] Term loan prepaid through November two two thousand twenty three. Term Loan Prepaid through November 2, 2023 [Member] Term Loan Prepaid Through November Two Two Thousand Twenty Three [Member] Variable Rate Variable Rate [Axis] Variable Rate Variable Rate [Domain] Prime Rate [Member] Prime Rate [Member] Subsequent Event [Line Items] Subsequent Event [Line Items] Borrowing amount Line Of Credit Facility Maximum Borrowing Capacity Line of credit facility additional discretionary. Loan, payment term Line Of Credit Facility Frequency Of Payment And Payment Terms Additional borrowing amount Line Of Credit Facility Remaining Borrowing Capacity Line of credit facility additional discretionary Line Of Credit Facility Additional Discretionary Line of credit Line Of Credit Line of credit facility additional prepayment of premium percentage. Line of credit facility prepayment of premium percentage. Loan maturity date Line Of Credit Facility Expiration Date1 Loan, interest rate Line Of Credit Facility Interest Rate During Period Line of credit facility prepayment of premium percentage Line Of Credit Facility Prepayment Of Premium Percentage Line of credit facility additional prepayment of premium percentage Line Of Credit Facility Additional Prepayment Of Premium Percentage