Cover [Abstract] Document Information [Table] Document Information [Line Items] Amendment Flag Amendment Flag City Area Code City Area Code Contact Personnel Name Document Type Document Type Entity Address, Address Line One Entity Address, Address Line One Entity Address, Address Line Two Entity Address, Address Line Two Entity Address, City or Town Entity Address, City or Town Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Address, State or Province Entity Address, State or Province Entity Central Index Key Entity Central Index Key Entity Emerging Growth Company Entity Emerging Growth Company Entity Filer Category Entity Filer Category Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity Primary SIC Number Entity Registrant Name Entity Registrant Name Entity Small Business Entity Small Business Entity Tax Identification Number Entity Tax Identification Number Local Phone Number Local Phone Number Entity Addresses, Address Type [Axis] Address Type [Domain] Business Contact [Member] Statement of Financial Position [Abstract] Assets [Abstract] Assets Assets Total assets Assets, Current [Abstract] Current assets: Assets, Current Total current assets Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and cash equivalents, end of period Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Prepaid expenses and other current assets Restricted Cash, Current Restricted cash Operating Lease, Right-of-Use Asset Operating lease assets Other Assets, Noncurrent Other assets Property, Plant and Equipment, Net Property and equipment, net Property and equipment, net Restricted Cash, Noncurrent Restricted cash, net of current portion Liabilities and Equity [Abstract] Liabilities and stockholders' equity Commitments and Contingencies Commitments and contingencies (Note 11) Liabilities Total liabilities Liabilities and Equity Total liabilities and stockholders' equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses and other current liabilities Accrued expenses Liabilities, Current Total current liabilities Operating Lease, Liability, Current Operating lease liabilities Notes Payable, Noncurrent Note payable, net of discount Note payable, net of discount, long-term Operating Lease, Liability, Noncurrent Operating lease liabilities, net of current portion Equity, Attributable to Parent [Abstract] Stockholders' equity: Additional Paid in Capital, Common Stock Additional paid-in capital Common Stock, Value, Issued Common stock, $0.0001 par value; 150,000 shares authorized as of December 31, 2023 and 2022; 44,654 and 43,916 shares issued and outstanding as of December 31, 2023 and 2022, respectively Preferred Stock, Value, Issued Preferred stock, $0.0001 par value; 10,000 shares authorized and no shares issued or outstanding as of December 31, 2023 and 2022 Retained Earnings (Accumulated Deficit) Accumulated deficit Equity, Attributable to Parent Total stockholders' equity Beginning balance Ending balance Common Stock, Par or Stated Value Per Share Common stock, par value Common stock, par value Common Stock, Shares Authorized Common stock, authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, issued Common Stock, Shares, Outstanding Common stock, outstanding Preferred Stock, Par or Stated Value Per Share Preferred stock, par value Preferred Stock, Shares Authorized Preferred stock, authorized Preferred Stock, Shares Issued Preferred stock, issued Preferred stock issued Preferred Stock, Shares Outstanding Preferred stock, outstanding Statement of Comprehensive Income [Abstract] Earnings Per Share, Basic Net income (loss) per share applicable to common stockholders-basic Earnings Per Share, Diluted Net income (loss) per share applicable to common stockholders diluted Income (Loss) Attributable to Noncontrolling Interest, before Tax Income (loss) before income taxes Income Tax Expense (Benefit) Provision for income tax expense Net Income (Loss) Net income (loss) and comprehensive income (loss) attributable to common stockholders-basic and diluted Net Income (Loss) Nonoperating Income (Expense) [Abstract] Other income (expense): Investment Income, Net Interest income (expense), net Nonoperating Income (Expense) Total other income (expense), net Other Nonoperating Expense Other expense, net Operating Expenses [Abstract] Operating expenses: Gain (Loss) on Impairment Loss on impairment Gain (Loss) on Impairment Gain (Loss) on Sale of Assets and Asset Impairment Charges Gain on asset sale General and Administrative Expense General and administrative Operating Expenses Total operating expenses Operating Income (Loss) Income (loss) from operations Research and Development Expense Research and development Research and development expense Weighted Average Number of Shares Outstanding, Diluted Weighted-average common shares outstanding-diluted Weighted Average Number of Shares Outstanding, Basic Weighted-average common shares outstanding basic Statement of Stockholders' Equity [Abstract] Statement [Table] Statement [Table] Equity Components [Axis] Equity Components Equity Component [Domain] Equity Component Additional Paid-in Capital [Member] Additional Paid-in Capital [Member] Common Stock [Member] Common Stock [Member] Retained Earnings [Member] Accumulated Deficit [Member] Statement [Line Items] Statement [Line Items] APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation expense Shares, Outstanding Beginning balance, shares Ending balance, shares Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock under 2018 employee stock purchase plan, shares Stock Issued During Period, Shares, Restricted Stock Award, Gross Vesting of restricted stock awards and units, shares Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercise of stock options, shares Number of options, Exercised Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock under 2018 employee stock purchase plan Stock Issued During Period, Value, Stock Options Exercised Exercise of stock options Sale of Stock [Axis] Sale of Stock Sale of Stock [Domain] Sale of Stock Statement of Cash Flows [Abstract] Plan Name [Axis] Plan Name [Domain] Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash, end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect [Abstract] Reconciliation of cash, cash equivalents and restricted cash reported within the consolidated balance sheets: Restricted Cash Restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase (decrease) in cash, cash equivalents and restricted cash Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non-cash investing and financing activities: Common Stock Offering Costs Incurred But Not Yet Paid Right of use asset obtained in exchange for operating lease liabilities Common stock offering costs incurred but not yet paid. Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities Net cash (used in) provided by financing activities Proceeds from Issuance of Common Stock Proceeds from issuance of common stock under 2018 employee stock purchase plan Proceeds from Stock Options Exercised Exercise of stock options Repayment of note payable, including end of term charge Repayment of note payable, including end of term charge Repayment of note payable, including end of term charge Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Proceeds from Sale of Buildings Proceeds from asset sale, net Proceeds from Sale of Property, Plant, and Equipments Proceeds from the sale of property, plant, and equipment Proceeds from Sale of Property, Plant, and Equipments Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Asset Impairment Charges Non-cash asset impairment charges Depreciation, Depletion and Amortization Depreciation and amortization expense (Gain)/loss on extinguishment of operating lease (Gain)/loss on extinguishment of operating lease (Gain)/loss on extinguishment of operating lease (Gain)/loss on impairment of leasehold improvements (Gain)/loss on impairment of leasehold improvements (Gain)/loss on impairment of leasehold improvements Gain (Loss) on Disposition of Property Plant Equipment Loss on disposal of property and equipment Gain on Sale of Investments Gain on asset sale Non Cash Interest Expense Non-cash interest expense Non-cash interest expense. Non-cash lease expense Non-cash lease expense Non-cash lease expense Other Noncash Income Tax Expense Non-cash income tax expense Share-Based Payment Arrangement, Noncash Expense Stock-based compensation expense Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Current and non-current operating lease liabilities Current and non-current operating lease liabilities Current and non-current operating lease liabilities Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Accrued expenses and other current liabilities Increase (Decrease) in Other Operating Assets Other assets Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net income (loss) Supplemental Cash Flow Information [Abstract] Supplemental Cash: Interest Paid, Excluding Capitalized Interest, Operating Activities Interest paid Organization, Consolidation and Presentation of Financial Statements [Abstract] Nature of Operations [Text Block] Nature of the Business Accounting Policies [Abstract] Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies License Agreements [Abstract] License agreements. License Agreement Disclosure [Text Block] License and Purchase Agreements License agreement disclosure. Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Fair Value of Financial Assets and Liabilities Balance Sheet Related Disclosures [Abstract] Supplemental Balance Sheet Disclosures [Text Block] Supplemental Balance Sheet Information Leases [Abstract] Lessor, Operating Leases [Text Block] Leases Debt Disclosure [Abstract] Debt Disclosure [Text Block] Note Payable Equity [Abstract] Stockholders' Equity Note Disclosure [Text Block] Common Stock Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Text Block] Stock-Based Compensation Retirement Benefits [Abstract] Retirement Benefits [Text Block] 401(k) Savings Plan Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Earnings Per Share [Abstract] Earnings Per Share [Text Block] Net Income (Loss) per Share Related Party Transactions [Abstract] Related Party Transactions Disclosure [Text Block] Related Party Transactions Restructuring and Related Activities [Abstract] Restructuring and Related Activities Disclosure [Text Block] Restructuring Subsequent Events [Abstract] Subsequent Events [Text Block] Subsequent Events Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Compensation Related Costs, Policy [Policy Text Block] Stock-Based Compensation Comprehensive Income, Policy [Policy Text Block] Comprehensive Income (Loss) Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentrations of Credit Risk Consolidation, Policy [Policy Text Block] Principles of Consolidation Earnings Per Share, Policy [Policy Text Block] Net Income (Loss) per Share Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements Foreign Currency Transactions and Translations Policy [Policy Text Block] Foreign Currency Translation Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] Impairment of Long-Lived Assets Income Tax, Policy [Policy Text Block] Income Taxes Lessee, Leases [Policy Text Block] Leases New Accounting Pronouncements, Policy [Policy Text Block] Recently Adopted Accounting Pronouncements Property, Plant and Equipment, Policy [Policy Text Block] Property and Equipment Research and Development Expense, Policy [Policy Text Block] Research and Development Expenses Segment Reporting, Policy [Policy Text Block] Segment Information Subsequent Events, Policy [Policy Text Block] Subsequent Event Considerations Use of Estimates, Policy [Policy Text Block] Use of Estimates Schedule Of Property Plant And Equipment Estimated Useful Life Table [Text Block] Schedule of Property and Equipment Estimated Useful Life Schedule Of Property Plant And Equipment Estimated Useful Life [Table Text Block] Fair Value Measurements, Recurring and Nonrecurring [Table Text Block] Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Summary of Prepaid Expenses and Other Current Assets Property, Plant and Equipment [Table Text Block] Summary of Property and Equipment, Net Schedule of Accrued Liabilities [Table Text Block] Summary of Accrued Expenses Restrictions on Cash and Cash Equivalents [Table Text Block] Summary of Restricted Cash Operating Lease, Lease Income [Table Text Block] Summary of Future Minimum Lease Payments Due Under Operating Leases