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Tectonic has developed a proprietary technology platform called GEODe™ to enable the discovery and development of GPCR-targeted biologic medicines that can modify the course of disease, by addressing challenges that have limited the pace of innovation in this field. Tectonic’s TX45 Fc-relaxin fusion protein is a potential best-in-class agent, resulting from protein engineering efforts to overcome limitations associated with the natural human hormone and achieve both optimal in vitro (biophysical and developability), as well as in vivo (pharmacokinetic and pharmacodynamic, or “PK/PD”) properties. Tectonic is leveraging relaxin’s vasodilatory and anti-fibrotic properties with the goal of improving treatment outcomes for patients with Group 2 pulmonary hypertension. Tectonic is headquartered in Watertown, Massachusetts. Learn more at www.tectonictx.com and follow us @TectonicTx.

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Our News Latest press releases

Aug 20, 2024

Tectonic Therapeutic to Participate in September Investor Conferences

WATERTOWN, Mass. , Aug. 20, 2024 (GLOBE NEWSWIRE) -- Tectonic Therapeutic, Inc. (NASDAQ: TECX) (Tectonic), a clinical stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs), today

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Aug 14, 2024

Tectonic Therapeutic Announces Second Quarter 2024 Financial Results and Recent Business Highlights

TX45 advances into Phase 2 clinical trial for patients with Group 2 PH-HFpEF with first site activated and screening open in August 2024 Received U.S. Investigational New Drug (IND) clearance for lead program, TX45 in July 2024 Completed reverse merger with AVROBIO in June 2024 , including

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Jul 30, 2024

Tectonic Therapeutic Announces US IND Clearance for Lead Program, TX45

TX45 is an Fc-relaxin fusion protein being evaluated in patients with Group 2 Pulmonary Hypertension (PH) due to Heart Failure with Preserved Ejection Fraction (HFpEF), a serious condition estimated to affect over 600,000 people in the U.S. alone, currently with no approved therapies Planned

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